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Table 1 Hepatitis C micro-elimination progress in target populations in the Netherlands in 2017

From: Strategies for achieving viral hepatitis C micro-elimination in the Netherlands

  Population size (N) HCV seroprevalence (%) Total chronic HCV infections (HCV RNA (+)) (N) HCV infections cured (N)/(%) Source/Comments Main actions/interventions to facilitate HCV elimination
HIV-infected 22,900 12% 1471 (R) 1124/76% [24, 27] • Behavioral counseling.
• Once in a lifetime or frequentc screening (depending on risk behavior).
Hemophilia patients (born < 1992) NA NA 700 (R) 190/27.1% [25] (Combined Dutch & UK cohort) • Once in a lifetime screening.
• Treatment scale-up.
High-risk MSM (HIV-negative)b NA 4,8% NA NA/NA [57] • Behavioral counseling.
• Frequentc screening
• Early treatment in case of (re) infection.
Migrants from high endemic countries 1,527,032 NA 13,819 (E) NA/NA [58] • Raise awareness of HCV through local/multimedia information campaigns.
• Once in a lifetime screening for first-generation migrants with HCV prevalence ≥2% in country of origin.
PWID 14,000 39–74% 4040–7666 (C) NA/NA [7, 12,13,14,15,16, 59] • Once in a lifetime or frequentc screening (depending on risk behavior).
• Treatment scale up.
Prisoners 10,194/each day 7.4–13.9% 558–1049 (C) NA/NA [60,61,62] • Educate prison doctors on HCV.
• Once in a lifetime or frequentc screening (depending on risk behavior).
• Include detainees in regular health insurance.
Hemodialysis patients 17,132 NA NA NA/NA [63] • Once in a lifetime screening.
Health care workersd NA NA NA NA/NA • Once in a lifetime screening by employer.
General Dutch population 17,081,507a 0.1–0.4% 12,640–50,561 (C) 4427/8–35% [7, 29] • Raise awareness of HCV through multimedia information campaigns.
• Educate general practitioners on HCV to increase compliance with viral hepatitis screening and referral guidelines.
• Trace and treat HCV infected lost to follow-up.
  1. PWID people who (have ever) inject(ed) drugs, MSM men who have sex with men, NA not available. (R) = reported numbers from publications of registries; (E) = estimated numbers reported in studies; (C) = calculated from seroprevalence estimates multiplied by .74 (assumed spontaneous clearance rate of 26%)
  2. a https://opendata.cbs.nl/statline/#/CBS/nl, Dutch population numbers in 2017
  3. b MSM with high-risk sexual activities
  4. c One to four times per year
  5. d Health care workers who perform hazardous tasks, putting them at risk for acquiring of transferring a hepatitis C infection (definition from the National Health Council) [4]