Skip to main content

Drug consumption rooms (DCRs) as a setting to address hepatitis C – findings from an international online survey



Prevalence of Hepatitis C Virus (HCV) among people who inject drugs (PWID) is high. Risky injecting behaviours have been found to decrease in drug consumption rooms (DCRs) and supervised injecting facilities (SIFs), yet HCV prevention and treatment in these settings have not been extensively explored.


To determine the range and scope of HCV prevention and treatment options in these services, we assessed DCR/SIF operational features, their clients’ characteristics and the HCV-related services they provide. A comprehensive online survey was sent to the managers of the 91 DCRs/SIFs that were operating globally as of September 2016. A descriptive cross-country analysis of the main DCR/SIF characteristics was conducted and bivariate logistic models were used to assess factors associated with enhanced HCV service provision.


Forty-nine valid responses were retrieved from DCRs/SIFs in all countries where they were established at the time of the survey (Australia, Canada, Denmark, France, Germany, Luxembourg, Netherlands, Norway, Spain and Switzerland). Internationally, the operational capacities of DCRs/SIFs varied in terms of funding, location, size and staffing, but their clients all shared common features of vulnerability and marginalisation. Estimated HCV prevalence rates were around 60%. Among a range of health and social services and referrals to other programs, most DCRs/SIFs provided HCV testing onsite (65%) and/or offered liver monitoring or disease management (54%). HCV treatment onsite was offered or was planned to be offered by 21% of DCRs/SIFs. HCV testing onsite was associated with provision of other services addressing blood-borne diseases and HCV treatment was linked to the provision of OST. HCV disease management was associated with employing a nurse at a DCR/SIF and HCV treatment was associated with employing a medical doctor.


DCRs/SIFs offer easy-to-access HCV-related services for PWID. The availability of onsite medical professionals and provision of support and education to non-medical staff are key to enhanced provision of HCV-related services in DCRs/SIFs. Funding and support for HCV treatment at the community level, via low-threshold services such as DCRs/SIFs, are worthy of action.


Drug consumption rooms (DCRs) / safe injecting facilities (SIFs) provide hygienic environments in which people who use/inject drugs (PWUD/PWID) can administer illegal drugs under the supervision of a health care professional, a trained allied service provider, or a peer (i.e., person who formerly used or currently uses illegal drugs), without the risk of arrest for drug possession [1]. DCRs/SIFs are evidence-based harm reduction interventions [2] with demonstrated effectiveness [3,4,5,6,7,8,9,10,11]. DCRs/SIFs generally target the most marginalised populations of people who use drugs (PWUD), people who inject drugs (PWID), and high-risk drug users (HRDU) [12, 13]. Studies among PWID have found that Hepatitis C Virus (HCV) prevalence at baseline is higher among DCR/SIF attendees than non-attendees [14], with daily attendees at greatest risk [15].

As such, DCRs/SIFs have the capacity to diagnose HCV among their clients in a timely way [16]. Several studies have documented the impact of DCRs/SIFs on HCV and HIV notifications [17,18,19], proving them cost-effective [20,21,22]. While decreases in risky injecting behaviour have been observed as an outcome of DCRs/SIFs attendance [23,24,25,26], HCV prevention and treatment in these settings has not been adequately explored in a cross-national context.

Recent research has demonstrated that high completion rates of HCV treatment among PWID [27], low rates of re-infection [28] and the provision of HCV treatment to active PWID are both effective and cost-effective [29, 30]. Adherence and response to the new, direct-acting antiviral agents (DAAs) therapy among PWID receiving opioid substitution treatment (OST) is comparable with people who never injected drugs [31], however numerous factors impede PWID participation in HCV treatment, including health system-related barriers, unstable housing or expectations of treatment side effects. Harm reduction services for PWID are an obvious avenue to circumventing some of these barriers [32] and can provide treatment-as-prevention [33], particularly to those clients attending on a daily basis or their “frequent attenders” [17, 34].

To date, surveys have not addressed HCV prevention and treatment among DCRs/SIFs clients [35, 36]. This study explored the range and scope of HCV-related services currently provided by DCRs/SIFs internationally, including HCV education, testing, disease management and treatment. We also explored their operational features and examined which factors were associated with the provision of enhanced HCV-related services at DCRs/SIFs.


To assess the range and scope of HCV-related services currently provided by the 91 DCRs/SIFs operating in 10 countries across the world at the time of this study (September – December 2016), an online survey was conducted. An invitation to participate in the study was sent to the mailing list of the International Network of Drug Consumption Rooms and of the Correlation Network (European Network for Social Inclusion and Health). The initial email requested a manager (or person in a similar position) completed the survey on behalf of the organisation. Managers were also asked to decline participation on behalf of their organization if they decided not to participate. Requests to participate were emailed three times to those who did not fill in the survey or did not respond (in October, November and early December 2016).

Survey questions focused on the DCRs/SIFs organisational structure and environment, staff composition and general client characteristics (18 items). Data on client characteristics were requested as an estimate in aggregated form. HCV-specific questions focused on (i) HCV-related onsite interventions and referrals (18 items), (ii) DCRs/SIFs client characteristics in relation to HCV (2 items), and (iii) barriers and facilitators to the expansion of HCV-related services (2 items). Open-ended questions like “other” or “please, specify” where included. The survey was distributed in English. German translation was available and when completed, answers were translated back to English and entered into the online tool by the study team.

The survey took approximately 45 min to complete. To facilitate survey completion, all answers were made non-compulsory, resulting in a different number of responses in each question. All participants provided consent and could withdraw from the study at any time. Ethics approval was granted by the South Eastern Sydney Local Health District Human Research Ethics Committee (16/258 LNR/16/POWH/482).

Study sample

The project used an exhaustive sampling method (i.e. approached all DCRs operating at the time of the survey). A total of 91 DCRs/SIFs from ten countries were invited to participate, namely from the Netherlands (n = 30 – number of DCRs in operation), Switzerland (n = 13), Germany (n = 24), Spain (n = 13), Norway (n = 1), Denmark (n = 5), Luxembourg (n = 1), Australia (n = 1), Canada (n = 1), and France (n = 2). In total, 86 survey responses were collected and from those, 37 were excluded from the analysis. Ten were excluded because they declined participation, nine due to duplicate responses, one response was from someone who wasn’t eligible to take part in the study (not a DCR representative) and 17 were excluded as there was missing data for greater than 50% of answers. The remaining valid responses (n = 49) represented 54% of the DCRs/SIFs in operation at the time of the study.

Among the survey responses that were included in the analysis, each country was represented, i.e. the Netherlands (n = 8), Switzerland (n = 7), Germany (n = 17), Spain (n = 9), Norway (n = 1), Denmark (n = 2), Luxembourg (n = 1), Australia (n = 1), Canada (n = 1) and France (n = 2) (Table 1). Responses were grouped according to DCF/SIF country of operation. The countries where only a few DCRs/SIFs operated (< 5) were included in the “remaining countries” category (n = 8).

Table 1 DCRs/ SIFs operating internationally and those who responded to the survey

Data and analysis

Client characteristics and service provision data were analysed using descriptive analysis. T-test and chi2 test were used to assess the difference in the mean values (for continuous variables) and in proportions (for categorical variables) between each country of operation and all other countries.

To explore the factors associated with HCV service provision, three outcome variables were considered: (1) provision of HCV testing onsite – saliva, finger prick, both, or other test, (2) provision of liver health monitoring (e.g. via fibro-scanning) and/or provision of support for HCV disease management, (3) provision of HCV treatment onsite (“new” treatments, interferon, or both) and/or planning to provide HCV treatment in the future. Bivariate logistic regression models were fitted in order to explore the statistical significance and size/direction of the relationship between outcome variables and a set of variables pertaining to DCRs/SIFs operational characteristics (unadjusted odds ratios were calculated). A range of operational characteristics were included in the bivariate logistic models as independent factors (Table 2).

Table 2 Per-country analysis of DCR/SIF characteristics (country vs. other; chi2 test, if not stated otherwise)


Descriptive Characteristics

DCRs/SIFs operational features

Most DCRs/SIFs were operated by a not-for-profit organisation (30/45, 67%). Other DCRs/SIFs providers included local, regional or national governments (18/45, 40%), private entities (3/45, 7%), or via contracts with a government (2/45, 4%) or religious organisation (n = 1). Services were funded from a variety of sources, often more than one. Funding was primarily provided by local (32/45, 71%), state/regional (16/45, 36%) or national (6/45, 13%) governments. Other funding sources included charities, drug service subsidies, donations or confiscated proceeds of crime.

The DCRs/SIFs were most commonly located in the centre of town (34/46, 74%), near a major travel hub (25/46, 54%) or within the boundaries of an established street-based drug scene (22/46, 48%). One fifth operated a mobile service (among those, two DCRs/SIFs operated a mobile service only). More than half were co-located with other services (26/46, 57%) and in four cases, these were shelters or overnight housing programs. About one third were stand-alone facilities, with other services used by their clients located nearby (14/46, 30%).

DCR/SIF capacities and services

The clinical staff at DCRs/SIFs included nurses (37/46, 80%), social workers (36/46, 78%), health educators/rescue workers (13/46, 35%) and medical doctors (20/46, 46%). Other professions employed by some DCRs/SIFs were psychiatrists, psychologists, case managers or researchers. Peers worked at one fifth and students / trainees in one sixth of the DCRs. About one third of DCRs/SIFs employed security personnel (15/46, 33%). Where estimated by the managers (n = 42), the average number of paid staff onsite on an average day was 7 (SD = 6.6, see Fig. 1 for details). A median of 10 spaces were offered for supervised drug consumption in DCRs/SIFs overall and the largest program had 63 spaces. See details of the operational capacities in Fig. 1.

Fig. 1
figure 1

Operational capacities of DCRs/SIFs

Beyond the supervision of the drug administration, a range of services composed the “core business” of DCRs/SIFs and these were distribution of needles and syringes for onsite and offsite use, onsite overdose management and provision of referrals to health and social services. The majority of DCRs/SIFs also provided onsite HIV-related counselling (31/46, 67%) and HIV testing (25/46, 54%). A SIFs provided/SIFs provided medical treatments onsite: OST (11/46, 24%), abstinence-oriented treatment (5/46, 11%), or HIV treatment (2/46, 4%). The health and the social services provided at DCRs/SIFs are summarized in Figures 2 and 3 respectively. It was common to refer clients elsewhere when services were not provided onsite.

Fig. 2
figure 2

Health services provided onsite and referred to offsite services by the DCRs/SIFs (n = 46)

Fig. 3
figure 3

Social services provided onsite and referred to offsite services by the DCRs/SIFs (n = 46)

HCV rates and other characteristics among DCR clients

A median of 78 visits were made at a DCR each day (mean = 108, SD = 120, n = 36) and the largest number of visits made at a DCR on an average day was in Denmark (550).

Forty-one DCRs in the study provided estimates of the proportion of their clients who had been tested for HCV (median = 80%) and who were HCV positive (median = 60%). The highest rates of HCV positive clients (80% and more) were estimated in nine DCRs from across all European countries except for the Netherlands and France. The proportion of clients with HIV was 6% (estimated median).

The median age of DCR/SIF clients was approximately 40 years old and most were male (median = 80%, n = 45). Most DCR/SIF clients were estimated to have ever entered drug treatment (median = 70%, n = 17) and to be on OST at the time of the survey (median = 60%, n = 27). About one third of clients (median 34%, n = 32) were estimated to be homeless. All characteristics of DCRs/SIFs clients who participated in the survey are summarized in Fig. 4.

Fig. 4
figure 4

DCR/SIF client characteristics, estimates reported by survey participants

HCV-specific services provided at DCRs/SIFs

In response to the HCV rates reported above and as a prevention measure, almost all DCRs/SIFs in the study indicated that they provided HCV-related education (46/49, 94%). This took various forms (educational materials, consultations) and focused on providing information about transmission routes, infection symptoms, testing or treatment options (Table 3). The majority of the DCRs/SIFs also offered HCV testing onsite (32/49, 65%). The testing was most commonly done through a blood sample, but also saliva and/or finger prick tests were performed. From those facilities that were not providing HCV testing onsite (n = 16), eight were planning to do so in the future and nine currently referred clients elsewhere.

Table 3 HCV education and testing provided onsite at DCRs/SIFs

Almost all DCRs/SIFs referred their clients to HCV treatment programmes (Table 4). More than half (25/46, 54%) offered enhanced HCV services in the form of liver monitoring or disease management (Table 4). About half (24/47, 51%) of the DCRs/SIFs in the study planned to expand HCV referrals or the enhanced support services in the future. Only four DCRs/SIFs provided HCV treatment onsite at the time of the survey (8%), two of them in the form of DAAs. Six additional services were planning to provide HCV treatment in the near future: either new treatments (n = 1), interferon treatment (n = 1) or an unspecified type of treatment (n = 4).

Table 4 HCV support services and treatment provided onsite at DCRs/SIFs and availability of HCV treatment to DCR clients

Differences between countries

The Dutch DCRs/SIFs (n = 8 of the 49) differed from other countries in a number of ways: they were receiving funding from local government (chi2 = 3.95, p = 0.047), they did not offer stand-alone programs, and, they operated with fewer paid employees (chi2 = 6.36, p = 0.012) and fewer nurses (chi2 = 5.70, p = 0.017) than other services surveyed. They also reported a lower number of visitors per day (t = 2.38, p = 0.01), and provided a lower estimate of HCV-positive clients (t = 3.03, p = 0.002). The Dutch DCRs/SIFs were also less likely to provide onsite HIV services (chi2 = 11.53, p = 0.00) or HCV testing (chi2 = 5.35, p = 0.02) than those located elsewhere.

German DCRs/SIFs (n = 17) differed from those in other countries in that a lower proportion of them offered HIV counselling (chi2 = 5.94, p = 0.015). Also unique to German DCRs was that they were less likely to be operated by the government (chi2 = 5.60, p = 0.018).

The Spanish DCRs/SIFs offered onsite HIV testing more often than others (chi2 = 5.38, p = 0.02), and also over-performed with respect to providing Naloxone training onsite (chi2 = 12.95, p = 0.00). The Spanish DCRs/SIFs (n = 9) tended to have fewer drug consumption spaces (t = 1.97, p = 0.03) than other countries. Also, the Spanish DCRs/SIFs estimated a significantly higher proportion of HCV positive clients (t = -1.80, p = 0.04).

Contrastingly, a higher number of drug consumption spaces (t = -3.46, p = 0.000) was reported by the Swiss DCRs/SIFs (n = 7). At the same time, the Swiss programs were less likely to employ a medical doctor (chi2 = 5.31, p = 0.021).

In the group of “remaining countries” (n = 8), employing a medical doctor (chi2 = 3.95, p = 0.048) was more common than elsewhere, they employed a higher number of staff (t = -1.83, p = 0.038) and were more commonly operated as stand-alone facilities (chi2 = 4.70, p = 0.030). They also had a significantly higher number of attendees on an average day (t = -1.79, p = 0.041). See Table 2 for a more detailed cross-national comparison.

Factors associated with provision of HCV services at DCRs/SIFs

HCV testing was conducted more frequently in DCRs that provided HIV testing (OR = 44.6, p = 0.00) or HBV vaccination (OR = 7.3, p = 0.01). Factors positively associated with HCV support (defined as provision of liver monitoring or disease management) onsite at the DCR/SIF were: onsite HIV counselling (OR = 4.1, p = 0.04), testing (OR = 7.0, p = 0.00) and HBV vaccination (OR = 6.7, p = 0.00), onsite OST (OR = 5.4, p = 0.03), and employment of a nurse (OR = 12.4, p = 0.01) or a medical doctor (OR = 8.0, p = 0.00). Current or future provision of HCV treatment onsite was significantly associated with employing a medical doctor (OR = 14.6, p = 0.00)  and marginally asssociated (OR = 4.3, p = 0.08) with provision of OST onsite (Table 5).

Table 5 Factors associated with HCV service provision at DCRs/SIFs - bi-variate logistic regression

When the managers were asked how they would spend any additional HCV-related funds, most said they would employ additional medical staff (24/46, 52%), develop client education around HCV (24/46, 52%) and/or provide additional staff training (21/46, 46%). Other responses included developing policies and procedures for staff, preparing educational material for clients or employing peer support workers. Conducting a needs assessment or developing referral pathways to a specialist were mentioned as well. Two organisations said that they would purchase a fibro-scan and one organisation mentioned that they would invest in advocacy to garner support to provide HCV treatment to “clandestine” persons.

When it comes to the reasons for not providing enhanced HCV-related services, some respondents indicated that HCV services were not part of the formal purpose of their facility (3/47, 6%). Other DCRs/SIFs mentioned that the site was already very busy or that the setting simply did not allow HCV services (n = 2), or that the DCRs/SIFs approach was non-medical and that current referral pathways worked well (n = 1). Other barriers included the high cost of rapid test kits (n = 1) or the fact that clients of the service were undocumented migrants who could not access treatment even if HCV positive.


This study explored the range and scope of HCV-related services currently provided by DCRs/SIFs internationally and examined associated factors. We found that prevention and management of blood-borne infections is a priority for the vast majority of the DCRs/SIFs that responded to this online survey. Most of them reported that they provided HCV-related education in some form and referred their clients to HCV testing and treatment. Over two thirds provided onsite HCV testing. Over half of those surveyed offered enhanced HCV support services that included liver-health monitoring or disease management. One fifth of the DCRs/SIFs in the study offered or planned to offer HCV treatment in the near future.

Current provision of enhanced HCV-related services was (with one exception) independent of the DCR/SIF country of origin, the DCR/SIF source of funding, any co-location with other programs, the size of the DCRs/SIFs or the actual HCV prevalence rates among their clients. Factors positively associated with HCV service provision were the provision of services related to blood-borne disease prevention and care, the provision of OST and the staff health and medical qualifications.

Internationally, the operational capacities of DCRs/SIFs vary, but their clients all share common features of marginalisation, including estimated HCV prevalence rates of about 60%. DCRs/SIFs are well positioned to support PWUD to access HCV-related services, given the ease of access and the established relations between staff and clients which support uptake and adherence to HCV treatment [37]. The fact that HCV testing was significantly more likely to occur in DCRs/SIFs that offered HIV testing, or that provided vaccination for HBV onsite, is of high importance for PWUD who often live with hepatitis and HIV co-infections [38].

In HCV management, non-invasive liver disease assessment (e.g. fibro-scanning) is recommended as a feasible method in out-patient settings for PWUDs, alongside individualised disease management within a multidisciplinary team [39]. Treatment as prevention can significantly reduce HCV prevalence among PWUD and while DAAs make this approach more feasible [39], combining it with OST improves its effectiveness and can reduce population-level HCV rates [40].

In the Netherlands, HCV incidence and chronicity rates among PWUD have been the lowest in the European region [41] and have been decreasing for some time [42] in response to intensive prevention and treatment efforts. The decreasing rates of drug injection in the Netherlands have likely contributed to this trend [43, 44]. It was unsurprising then that the Dutch DCRs/SIFs were less likely to provide HCV testing and related services pertaining to blood-borne diseases.

There were other per-country differences in DCR operational characteristics. For instance, it has long been part of the Dutch DCR concept to run smaller facilities in multiple neighbourhoods and to co-locate them with other services, rather than one large stand-alone facility in a central area [45]. In contrast, our findings show countries with few DCRs/SIFs are more likely to operate as stand-alone services (for example, the Medically Supervised Injecting Centre in Sydney, Australia).

Between 2017 and 2018, about thirty new DCRs/SIFs were approved in Canada (in addition to Insite in Vancouver) [46]. The operational, financial and public health considerations of establishing additional DCRs/SIFs seem to favor smaller facilities which are well-integrated within existing agencies [47]. This study indicated that stand-alone facilities require larger investments in personnel, including medical staff. The advantage of the co-located services is that they can support PWUD/PWID directly with relevant care onsite.

When looking at the determinants of HCV service provision, these don’t imply any causality and several other, unmeasured factors might play an important role. For instance, Australia has adopted universal access to HCV treatment, which is unprecedented internationally. Also, the Australian SIF employs a medical doctor. However, HCV treatment is not provided at the Sydney SIF, given the regulations around prescribing authority and it’s close cooperation with a nearby health service. On the other hand, the local-level funding of DCRs in the Netherlands may have led to substantial local-level variability in operating procedures and funding priorities, including HCV provision. Local policies play an obvious role in the level of HCV service provision but this study wasn’t designed to explore that in detail.

Low-threshold, harm reduction services such as DCRs/SIFs aim to “meet individuals where they are” in order to reduce individual and community-level harmful effects of drug use. Some clients might be systematically “falling through the net” of support services, leaving DCRs/SIFs the only programs they attend on a regular basis. This study found that HCV management and treatment were marginally more likely to be offered by DCRs/SIFs which also ran OST onsite. Unsurprisingly, the capacity to provide enhanced HCV care was closely related to the qualifications of DCRs/SIFs staff. Provision of liver monitoring or disease management were significantly associated with employing a nurse whereas HCV treatment was associated with employing a medical doctor. Enhancing staff qualifications via continuous education and greater engagement of health professionals in DCRs/SIFs operations will lead to more advanced HCV service provision and to continued engagement of the most vulnerable clients.

However, it needs to be acknowledged that hiring medical staff can represent a notable organisational and financial challenge for many DCRs/SIFs who are mostly funded outside of the general health funding schemes (e.g. local government budgets). Innovative protocols for the delivery of DAA treatments can include empowering existing staff via education and training to facilitate their cooperation with external medical professionals. In a recent Australian study, case managers who were supported by onsite nurses and medical doctors delivered DAA treatment in the community and achieved high completion rates [48]. This model can serve as an example for delivering flexible, patient-centred and cost-effective HCV treatment on community level. An additional barrier to implementing HCV treatments in DCRs might be the affordability of the medication. While the cost of medication is fully covered in Australia [49, 50], this has not been the situation in many low- and middle- income countries [51].

This study is limited by the relatively high non-response rate to the online survey (46%). Completing an online survey competes with other priorities and in some cases, filling in the survey was interrupted multiple times. In other instances, questions that required additional research into the DCR/SIF’s internal resources were skipped.

The DCRs/SIFs that did not participate in the survey (n = 52) may offer different services to specific client groups, depending on their location and purpose, or have lower operational capacity. Some DCRs/SIFs in the study mentioned that enhanced provision of HCV-related services was not a key purpose of their operation. It is possible that DCRs/SIFs with greater affinity for HCV service provision chose to answer the survey. Beyond this survey, there is no official source of information that could be used to cross-validate the representativity of the sample. An important limitation to this study is that the survey wasn’t available in all national languages (e.g. Spanish, Dutch, Danish or Norwegian) and misrepresentation of questions may have occurred.


The high infection rates of HCV among the DCRs/SIFs clients and the fact that HCV treatment as prevention can significantly reduce HCV rates among the population of PWUD warrant the attention for DCRs/SIFs to be seen as a potential space for the provision of HCV related services worldwide.

With their ease of access (‘low threshold’) and the regularity with which some clients attend them, DCRs/SIFs offer an important entry point to HCV treatment as well as a candidate program for the provision of new, DAA treatments. DCRs/SIFs can offer easy-to-access services and a trusted environment that is crucial in achieving HCV treatment adherence.

The main steps forward to enhance the onsite provision of HCV-related support in DCRs/SIFs are increasing their capacity to accommodate onsite medical professionals and educating existing staff. Funding and support for HCV treatment at the community level, via low-threshold services such as DCRs/SIFs, is worthy of action.



Direct acting antivirals


Drug consumption room


Hepatitis B virus


Hepatitis C virus


Human immunodeficiency virus


Opioid substitution treatment


People who inject drugs


People who use drugs


Supervised injecting facility


  1. BCCS. Supervised consumption services: operational guidance. In: Edited by the steering Committee for the Supervised Consumption Services Guidelines. British Columbia: British Columbia Centre on Substance Use, Ministry of Health; 2018.

    Google Scholar 

  2. EMCDDA. Drug consumption rooms: an overview of provision and evidence. In: Perspectives on drugs. Lisbon: European Monitoring Centre for Drugs and Drug Addiction; 2016.

    Google Scholar 

  3. Hedrich D, Hartnoll R. Harm reduction interventions. Textbook of Addiction Treatment: International Perspectives. 2015:1291–313.

  4. Hedrich D, Kerr T, Dubois-Arber F. Drug consumption facilities in Europe and beyond. In: Rhodes T, Hedrich D, editors. EMCDDA Scientific Monograph Series No 10- Harm Reduction: Evidence, Impacts and Challenges. Lisbon: The European Monitoring Centre for Drugs and Drug Addiction (EMCDDA); 2010.

    Google Scholar 

  5. Kerr T, Kimber J, DeBeck K, Wood E. The role of safer injection facilities in the response to HIV/AIDS among injection drug users. Current HIV/AIDS Reports. 2007;4(4):158–64.

    Article  PubMed  Google Scholar 

  6. Kimber J, Dolan K, Van Beek I, Hedrich D, Zurhold H. Drug consumption facilities: an update since 2000. Drug and Alcohol Review. 2003;22(2):227–33.

    Article  PubMed  CAS  Google Scholar 

  7. Kimber J, Palmateer N, Hutchinson S, Hickman M, Goldberg D, Rhodes T. Harm reduction among injecting drug users-evidence of effectiveness. In: Rhodes T, Hedrich D, editors. Harm Reduction: evidence, impacts and challenges. Lisbon: EMCDDA; 2010. p. 115–63.

    Google Scholar 

  8. Milloy MJ, Wood E. Emerging role of supervised injecting facilities in human immunodeficiency virus prevention. Addiction. 2009;104(4):620–1.

    Article  PubMed  Google Scholar 

  9. Monico D. Out of the alley: lessons from safe injecting facilities (SIF). Graduate Annual. 2015;3(1):12.

    Google Scholar 

  10. Potier C, Laprévote V, Dubois-Arber F, Cottencin O, Rolland B. Supervised injection services: what has been demonstrated? A systematic literature review. Drug Alcohol Depend. 2014;145:48–68.

    Article  PubMed  Google Scholar 

  11. Semaan S, Fleming P, Worrell C, Stolp H, Baack B, Miller M. Potential role of safer injection facilities in reducing HIV and hepatitis C infections and overdose mortality in the United States. Drug Alcohol Depend. 2011;118:11.

    Article  Google Scholar 

  12. Wood E, Tyndall MW, Li K, Lloyd-Smith E, Small W, Montaner JSG, Kerr T. Do supervised injecting facilities attract higher-risk injection drug users? Am J Prev Med. 2005;29(2):126–30.

    Article  PubMed  Google Scholar 

  13. van Beek I, Kimber J, Dakin A, Gilmour S. The Sydney medically supervised injecting Centre: reducing harm associated with heroin overdose. Crit Public Health. 2004;14(4):391–406.

    Article  Google Scholar 

  14. Bravo MJ, Royuela L, De la Fuente L, Brugal MT, Barrio G, Domingo-Salvany A, Itínere project group. Use of supervised injection facilities and injection risk behaviours among young drug injectors. Addiction. 2009;104(4):614–9.

    Article  PubMed  Google Scholar 

  15. Wood E, Tyndall MW, Qui Z, Zhang R, Montaner JSG, Kerr T. Service uptake and characteristics of injection drug users utilizing north Americas first medically supervised safer injecting facility. Am J Public Health. 2006;96(5):770–3.

    Article  PubMed  PubMed Central  Google Scholar 

  16. Parés-Badell O, Espelt A, Folch C, Majó X, González V, Casabona J, Brugal MT. Undiagnosed HIV and hepatitis C infection in people who inject drugs: from new evidence to better practice. J Subst Abus Treat. 2017;77:13–20.

    Article  Google Scholar 

  17. KPMG. Further evaluation of the Medically Supervised Injecting Centre during its extended trial period (2007-2011): Final report. Sydney: KPMG. p. 2010.

  18. MSIC Evaluation committee. Final report of the evaluation of the Sydney medically supervised injecting Centre. Sydney: Authors; 2003.

    Google Scholar 

  19. Salmon AM, van Beek I, Amin J, Grulich A, Maher L. High HIV testing and low HIV prevalence among injecting drug users attending the Sydney medically supervised injecting Centre. Aust N Z J Public Health. 2009;33(3):280–3.

    Article  PubMed  Google Scholar 

  20. Andresen MA, Boyd N. A cost-benefit and cost-effectiveness analysis of Vancouver's supervised injection facility. International Journal of Drug Policy. 2010;21(1):70–6.

    Article  PubMed  Google Scholar 

  21. Bayoumi AM, Zaric GS. The cost-effectiveness of Vancouver's supervised injection facility. Can Med Assoc J. 2008;179(11):1143–51.

    Article  Google Scholar 

  22. Pinkerton SD. Is Vancouver Canada's supervised injection facility cost-saving? Addiction. 2010;105(8):1429–36.

    Article  PubMed  Google Scholar 

  23. Stoltz J-A, Wood E, Small W, Li K, Tyndall M, Montaner J, Kerr T. Changes in injecting practices associated with the use of a medically supervised safer injection facility. Journal of Public Health. 2007;29(1):35–9.

    Article  PubMed  Google Scholar 

  24. Wood E, Tyndall MW, Stoltz J-A, Small W, Lloyd-Smith E, Zhang R, Montaner JSG, Kerr T. Factors Associated with Syringe Sharing Among Users of a Medically Supervised Safer Injecting Facility. American Jounral of Infectious Diseases. 2005:1(1).

  25. Kinnard EN, Howe CJ, Kerr T, Hass VS, Marshall BD. Self-reported changes in drug use behaviors and syringe disposal methods following the opening of a supervised injecting facility in Copenhagen Denmark. Harm Reduct J. 2014;11(1):1.

    Article  Google Scholar 

  26. Zurhold H, Degkwitz P, Verthein U, Haasen C. Drug consumption rooms in Hamburg, Germany: evaluation of the effects on harm reduction and the reduction of public nuisance. J Drug Issues. 2003;33(3):663–88.

    Article  Google Scholar 

  27. Dimova RB, Zeremski M, Jacobson IM, Hagan H, Des Jarlais DC, Talal AH. Determinants of hepatitis C virus treatment completion and efficacy in drug users assessed by meta-analysis. Clin Infect Dis. 2013;56(6):806–16.

    Article  PubMed  CAS  Google Scholar 

  28. Grady BP, Schinkel J, Thomas XV, Dalgard O. Hepatitis C virus reinfection following treatment among people who use drugs. Clin Infect Dis. 2013;57(suppl 2):S105–10.

    Article  PubMed  Google Scholar 

  29. Martin NK, Vickerman P, Miners A, Foster GR, Hutchinson SJ, Goldberg DJ, Hickman M. Cost-effectiveness of hepatitis C virus antiviral treatment for injection drug user populations. Hepatology. 2012;55(1):49–57.

    Article  PubMed  Google Scholar 

  30. Visconti AJ, Doyle JS, Weir A, Shiell AM, Hellard ME. Assessing the cost-effectiveness of treating chronic hepatitis C virus in people who inject drugs in Australia. J Gastroenterol Hepatol. 2013;28(4):707–16.

    Article  PubMed  Google Scholar 

  31. Grebely J, Hajarizadeh B, Dore GJ. Direct-acting antiviral agents for HCV infection affecting people who inject drugs. Gastoenterology & Hepatology. 2017;1:1–11.

    Google Scholar 

  32. McGowan CE, Fried MW. Barriers to hepatitis C treatment. Liver Int. 2012;32(s1):151–6.

    Article  PubMed  PubMed Central  CAS  Google Scholar 

  33. Dillon JF, Lazarus JV, Razavi HA. Urgent action to fight hepatitis C in people who inject drugs in Europe. Hepatology, Medicine and Policy. 2016;1(2):1–10.

    Google Scholar 

  34. Dubois-Arber F, Benninghoff F, Jeannin A. Typology of injection profiles of clients of a supervised drug consumption facility in Geneva Switzerland. European Addiction Research. 2008;14(1):1–10.

    Article  PubMed  Google Scholar 

  35. Woods S. Organisational overview of drug consumption rooms in Europe. Amsterdam: European Harm Reduction Network – Regenboog Groep; 2014.

    Google Scholar 

  36. Kimber JO, Dolan K, Wodak A. Survey of drug consumption rooms: service delivery and perceived public health and amenity impact. Drug and Alcohol Review. 2005;24(1):21–4.

  37. Rich ZC, Chu C, Mao J, Zhou K, Cai W, Ma Q, Volberding P, Tucker JD. Facilitators of HCV treatment adherence among people who inject drugs: a systematic qualitative review and implications for scale up of direct acting antivirals. BMC Public Health. 2016;16(1):994.

    Article  PubMed  PubMed Central  Google Scholar 

  38. Nielsen S, Gassowski M, Wenz B, Bannert N, Bock C-T, Kücherer C, Ross RS, Bremer V, Marcus U, Zimmermann R. Concordance between self-reported and measured HIV and hepatitis C virus infection status among people who inject drugs in Germany. Hepatology, Medicine and Policy. 2016;1(1):8.

    Article  PubMed  PubMed Central  Google Scholar 

  39. Grebely J, Robaeys G, Bruggmann P, Aghemo A, Backmund M, Bruneau J, Byrne J, Dalgard O, Feld JJ, Hellard M. Recommendations for the management of hepatitis C virus infection among people who inject drugs. International Journal of Drug Policy. 2015;26(10):1028–38.

    Article  PubMed  Google Scholar 

  40. Martin NK, Hickman M, Hutchinson SJ, Goldberg DJ, Vickerman P. Combination interventions to prevent HCV transmission among people who inject drugs: modeling the impact of antiviral treatment, needle and syringe programs, and opiate substitution therapy. Clinical Infectious Diseases. 2013;57(suppl_2):S39–45.

    Article  PubMed  PubMed Central  Google Scholar 

  41. Wiessing L, Ferri M, Grady B, Kantzanou M, Sperle I, Cullen KJ, Hatzakis A, Prins M, Vickerman P, Lazarus JV. Hepatitis C virus infection epidemiology among people who inject drugs in Europe: a systematic review of data for scaling up treatment and prevention. PLoS One. 2014;9(7):e103345.

    Article  PubMed  PubMed Central  CAS  Google Scholar 

  42. van de Laar TJ, Molenkamp R, van den Berg C, Schinkel J, Beld MG, Prins M, Coutinho RA, Bruisten SM. Frequent HCV reinfection and superinfection in a cohort of injecting drug users in Amsterdam. J Hepatol. 2009;51(4):667–74.

    Article  PubMed  Google Scholar 

  43. Van Ameijden E, Coutinho R. Large decline in injecting drug use in Amsterdam, 1986–1998: explanatory mechanisms and determinants of injecting transitions. J Epidemiol Community Health. 2001;55(5):356–63.

    Article  PubMed  PubMed Central  CAS  Google Scholar 

  44. van de Laar TJ, Langendam MW, Bruisten SM, Welp EA, Verhaest I, van Ameijden EJ, Coutinho RA, Prins M. Changes in risk behavior and dynamics of hepatitis C virus infections among young drug users in Amsterdam, the Netherlands. J Med Virol. 2005;77(4):509–18.

    Article  PubMed  CAS  Google Scholar 

  45. Dolan K, Kimber J, Fry C, McDonald D, Fitzgerald J, Trautmann F. Drug consumption facilities in Europe and the establishment of supervised injecting centres in Australia. Drug and Alcohol Review. 2000;19(3):337–46.

    Article  Google Scholar 

  46. Health Canada. Supervised consumption sites: status of applications. Vancouver: Government of Canada; 2018.

    Google Scholar 

  47. Williams S: Opinion: Safe injection sites a small step but big milestone in saving lives. In: Edmonton Journal. vol. 25th October, 2017. Edmonton; 2017., Retrieved on 30th July, 2018.

  48. Morris L, Smirnov A, Kvassay A, Leslie E, Kavanagh R, Alexander N, Davey G, Williams O, Gilks C, Najman J. Initial outcomes of integrated community-based hepatitis C treatment for people who inject drugs: findings from the Queensland injectors’ health network. Int J Drug Policy. 2017;47:216–20.

    Article  PubMed  Google Scholar 

  49. Lazarus JV. Edito-in-Chief’s welcome to Hepatology, medicine and policy. BMJ Hepatology, Medicine and Policy. 2016;1(1):1–3.

    Article  Google Scholar 

  50. Iyengar S, Tay-Teo K, Vogler S, Beyer P, Wiktor S, de Joncheere K, Hill S. Prices, costs, and affordability of new medicines for hepatitis C in 30 countries: an economic analysis. PLoS Med. 2016;13(5):e1002032.

    Article  PubMed  PubMed Central  Google Scholar 

  51. FitzSimons D, Hendrickx G, Hallauer J, Larson H, Lavanchy D, Lodewyckx I, Shouval D, Ward J, Van Damme P. Innovative sources for funding of viral hepatitis prevention and treatment in low-and middle-income countries: a roundtable meeting report. Hepatology, Medicine and Policy. 2016;1(1):16.

    Article  PubMed  PubMed Central  Google Scholar 

Download references


The authors would like to thank all DCR/SIF managers who participated in the study. They would also like to thank Associate Professor Carolyn Day and Dr. Edmund Silins for providing comments to the manuscript, to Dr Libby Topp for reviewing the study questionnaire and protocol.


No specific funding was obtained to conduct this study.

Availability of data and materials

Please contact author for data requests.

Author information

Authors and Affiliations



AS and ES designed the study. All the authors (VB, AS, ES, MJ) contributed to developing the study tools and protocols. VB conducted data analysis and prepared the draft manuscript. All authors (VB, AS, ES, MJ) contributed to interpretation of the findings and to the writing of the manuscript. All authors read and approved the final manuscript.

Corresponding author

Correspondence to Vendula Belackova.

Ethics declarations

Ethics approval and consent to participate

Ethics approval was by the South Eastern Sydney Local Health District Human Research Ethics Committee (16/258 LNR/16/POWH/482).

Consent for publication

Not applicable.

Competing interests

The authors declare that they have no competing interests.

Publisher’s Note

Springer Nature remains neutral with regard to jurisdictional claims in published maps and institutional affiliations.

Rights and permissions

Open Access This article is distributed under the terms of the Creative Commons Attribution 4.0 International License (, which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver ( applies to the data made available in this article, unless otherwise stated.

Reprints and permissions

About this article

Check for updates. Verify currency and authenticity via CrossMark

Cite this article

Belackova, V., Salmon, A.M., Schatz, E. et al. Drug consumption rooms (DCRs) as a setting to address hepatitis C – findings from an international online survey. Hepatology Medicine Policy 3, 9 (2018).

Download citation

  • Received:

  • Accepted:

  • Published:

  • DOI: